Afferent neurourology: A novel paradigm.
نویسنده
چکیده
The term "afferent neurourology" is introduced to describe the study of sensory processing related to the genitourinary tract. Urologic disorders that are characterized by abnormal sensory processing are reviewed, and unique challenges to our understanding of these disorders are described. A paradigm which separates afferent urologic disorders from efferent disorders and structural abnormalities is presented.
منابع مشابه
Changes in afferent activity after spinal cord injury.
AIMS To summarize the changes that occur in the properties of bladder afferent neurons following spinal cord injury. METHODS Literature review of anatomical, immunohistochemical, and pharmacologic studies of normal and dysfunctional bladder afferent pathways. RESULTS Studies in animals indicate that the micturition reflex is mediated by a spinobulbospinal pathway passing through coordinatio...
متن کاملModels for sensory neurons of dorsal root ganglia and stress urinary incontinence.
AIMS To discuss (1) animal models for investigating bladder afferent pathways from the spinal cord to the brain and (2) animal models of stress urinary incontinence (SUI) with a special emphasis on functional and histopathological characteristics of each model. METHODS Literature review of spinal mechanisms of bladder afferent pathways and animal models of SUI. RESULTS Electrophysiological ...
متن کاملResearching bladder afferents-determining the effects of β(3) -adrenergic receptor agonists and botulinum toxin type-A.
A substantial portion of the current research on lower urinary tract dysfunction is focused on afferent mechanisms. The main goals are to define and modulate the signaling pathways by which afferent information is generated, enhanced and conveyed to the central nervous system. Alterations in bladder afferent mechanisms are a potential source of voiding dysfunction and an emerging source for dru...
متن کاملEffects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat.
AIMS Transient receptor potential vanilloid 4 (TRPV4) may affect afferent pathways innervating the bladder. We investigated the effects of GSK1016790A (GSK) and RN1734, a TRPV4 agonist and antagonist, respectively, and P2X-purinoceptor antagonists (TNP-ATP and PPADS) on cystometry (CMG), and the effect of GSK on single afferent fiber activities (SAAs) of the rat bladder and its relationship wit...
متن کاملA novel vedic divider based crypto-hardware for nanocomputing paradigm: An extended perspective
Restoring and non-restoring divider has become widely applicability in the era of digital computing application due to its computation speed. In this paper, we have proposed the design of divider of different architecture for the computation of Vedic sutra based. The design of divider in the Vedic mode results in high computation throughput due to its replica architecture, where latency is mini...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Neurourology and urodynamics
دوره 29 Suppl 1 شماره
صفحات -
تاریخ انتشار 2010